[ incidence of co-occurrence of chlamydial cervicitis with bacterial vaginosis]

Bacterial vaginosis is caused by an imbalance in normal vaginal bacterial flora mainly caused by the introduction of pathogenic bacteria. Failure to properly treat this condition cannot only induce abortion but also increase the chance of acquiring other serious infections such as AIDS, gonorrhea and chlamydiosis. Chlamydia trchomatis is one of the causative agents of cervicitis of which 70% is totally asymptomatic. Untreated cases can lead to salpengititis, pelvic inflammatory diseases, infertility, pelvic area pains and other complications. The purpose of this study was to determine the co-occurrence of these two conditions. A total of 137 patients were examined for both Chlamydial cervicitis and for bacterial vaginosis. Gram stain was used to detect bacterial vaginosis and anti-chlamydial antibodies were titered by microimmunofluoresence [MIF] assay. According to the MIF results, 10 patients [7.3%] had elevated anti-chlamydial IgG and 3 patients [2.2%] showed high IgM titers. Gardnerella vaginalis was detected in 6 patients [4.7%] as the causative agent of vaginosis. There were 3 cases of co-occurrence of chlamydial cervicitis and bacterial vaginosis [30%]. Due to the fact that bacterial vaginosis can provide the pre-disposing conditions for cervicitis and its chronicity and the similarity of the cilinical singns of these two conditions, Infections with Chlamydia are often overlooked. It therefore seems necessary to check any patient with bacterial vaginosis for chlamydial co-infection

frequency of hearing loss etiology among deaf students in Chaharmahal va Bakhtiari province, Iran, 2008-2009

Hearing loss is the most common sensory disorder in human and has a profound economic and social impact in the modern world. The etiology of deafness can be due to genetic or non-genetic causes in origin. Genetics etiology of hearing loss is classified into syndromic and nonsyndromic. The aim of this study was to determine the etiology of deafness in deaf students in Chaharmahal va Bakhtiari province, Iran. Altogether, 265 patients with mild to profound hearing loss were contributed in this descriptive study. The subjects were deaf pupils from the schools of Chaharmahal va Bakhtiari province. Age of the students was between 6 and 22 years. Medical history, pedigree information and demographic data were collected using a questionnaire. Each patient underwent general and otoscopic examinations and also pure-tone audiometery. Otoacoustic emissions, as well as auditory brainstem response testing were performed in patients suspected to neural hearing loss. Consanguineous marriages were detected in 67.2% of deaf families, from which first cousins marriage was the most common with the rate of 78.1% of overall consanguinity. Our study revealed that up to 98.8% of genetic deafness cases were in autosomal recessive mode. We found sensorineural hearing loss as a predominant type of deafness in 97.8% of the population studied. Moreover, hearing loss with genetic in origin was found as the most frequent deafness etiology with a rate of 60.8% and then acquired and idiopathic hearing loss are in next step, respectively. We found syndromic etiology in 4.2% of the students and ophthalmic problems were the most dysfunction accompanied with hearing loss. This data highlight the importance of consanguine marriage in the studied population. We found a very high rate [67.2%] of consanguine marriage, which can be the main cause of congenital deafness

Endometrial cancer consisting of both adenosquamous and serous papillary cells with raised beta-hCG: a case report

A 69-year old menopause woman presented with severe vaginal bleeding lasting for 70 days. Sonographist reported a 7mm mass in uterus, however, serologic studies revealed an elevated beta-hCG level. Patient was subjected for total hysterectomy and bilateral salpingoophorectomy, during which endometrial cancer tissue consisting of both adenosquamous and serous papillary cells were noted. beta-hCG level is rarely supposed to elevate in endometrial cancer, however, its association with endometrial cancer should be further discussed